Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

Contributors

This material was contributed to by:

Mélanie Petera avatar Mélanie Peteraorcid logoBérénice Batut avatar Bérénice Batutorcid logoFlorian Heyl avatar Florian HeylFriederike Dündar avatar Friederike Dündarorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoLucille Delisle avatar Lucille DelisleWilliam Durand avatar William Durandorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczTorsten Houwaart avatar Torsten HouwaartFidel Ramirez avatar Fidel RamirezDevon Ryan avatar Devon Ryanorcid logoArmin Dadras avatar Armin Dadrasorcid logoMaria Doyle avatar Maria Doyleorcid logoMallory Freeberg avatar Mallory FreebergJoachim Wolff avatar Joachim Wolfforcid logoBjörn Grüning avatar Björn Grüningorcid logoNicola Soranzo avatar Nicola SoranzoVerena Moosmann avatar Verena Moosmannorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoMo Heydarian avatar Mo Heydarianorcid logoPavankumar Videm avatar Pavankumar VidemEkaterina Polkh avatar Ekaterina Polkhorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoHelena Rasche avatar Helena Rascheorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoYvan Le Bras avatar Yvan Le BrasNiall Beard avatar Niall BeardVivek Bhardwaj avatar Vivek BhardwajMehmet Tekman avatar Mehmet TekmanLeily Rabbani avatar Leily RabbaniAnup Kumar avatar Anup Kumarorcid logoMartin Čech avatar Martin Čechorcid logoKatarzyna Kamieniecka avatar Katarzyna KamienieckaGildas Le Corguillé avatar Gildas Le Corguillé

Funding

These individuals or organisations provided funding support for the development of this resource

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CRC992
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UFR
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ELIXIR Europe
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de.NBI