Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

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Contributors

This material was contributed to by:

orcid logoMallory Freeberg avatar Mallory Freebergorcid logoAnika Erxleben avatar Anika ErxlebenDevon Ryan avatar Devon Ryanorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczJoachim Wolff avatar Joachim WolffFriederike Dündar avatar Friederike Dündarorcid logoWolfgang Maier avatar Wolfgang MaierMélanie Petera avatar Mélanie PeteraWilliam Durand avatar William DurandEkaterina Polkh avatar Ekaterina Polkhorcid logoHelena Rasche avatar Helena Rascheorcid logoBjörn Grüning avatar Björn GrüningLeily Rabbani avatar Leily RabbaniFidel Ramirez avatar Fidel Ramirezorcid logoKatarzyna Kamieniecka avatar Katarzyna KamienieckaVivek Bhardwaj avatar Vivek Bhardwajorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoLucille Delisle avatar Lucille Delisleorcid logoTristan Reynolds avatar Tristan Reynoldsorcid logoMaria Doyle avatar Maria DoyleVerena Moosmann avatar Verena Moosmannorcid logoMo Heydarian avatar Mo Heydarianorcid logoHans-Rudolf Hotz avatar Hans-Rudolf HotzTorsten Houwaart avatar Torsten Houwaartorcid logoCristóbal Gallardo avatar Cristóbal Gallardoorcid logoMartin Čech avatar Martin ČechMehmet Tekman avatar Mehmet TekmanGildas Le Corguillé avatar Gildas Le Corguilléorcid logoPavankumar Videm avatar Pavankumar Videmorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoFlorian Heyl avatar Florian Heylorcid logoArmin Dadras avatar Armin Dadrasorcid logoAnup Kumar avatar Anup Kumarorcid logoKhaled Jum'ah avatar Khaled Jum'ahNiall Beard avatar Niall Beardorcid logoBérénice Batut avatar Bérénice Batut

Funding

These individuals or organisations provided funding support for the development of this resource

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ELIXIR Europe
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Collaborative Research Centre 992
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Australian BioCommons
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UFR
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Melbourne Bioinformatics
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de.NBI
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The University of Melbourne