Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim WolffDevon Ryan avatar Devon Ryan

Contributors

This material was contributed to by:

orcid logoMallory Freeberg avatar Mallory FreebergNiall Beard avatar Niall Beardorcid logoMo Heydarian avatar Mo Heydarianorcid logoYvan Le Bras avatar Yvan Le BrasJoachim Wolff avatar Joachim WolffFidel Ramirez avatar Fidel Ramirezorcid logoHelena Rasche avatar Helena Rascheorcid logoFlorian Heyl avatar Florian HeylFriederike Dündar avatar Friederike DündarLeily Rabbani avatar Leily RabbaniEkaterina Polkh avatar Ekaterina Polkhorcid logoSaskia Hiltemann avatar Saskia HiltemannMehmet Tekman avatar Mehmet Tekmanorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczDevon Ryan avatar Devon Ryanorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoMaria Doyle avatar Maria DoyleVivek Bhardwaj avatar Vivek BhardwajMélanie Petera avatar Mélanie Peteraorcid logoBérénice Batut avatar Bérénice Batutorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoBjörn Grüning avatar Björn GrüningTorsten Houwaart avatar Torsten Houwaartorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoPavankumar Videm avatar Pavankumar VidemAnup Kumar avatar Anup Kumarorcid logoLucille Delisle avatar Lucille Delisle

Funding

These individuals or organisations provided funding support for the development of this resource

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ELIXIR Europe
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de.NBI
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UFR
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CRC992