Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

Contributors

This material was contributed to by:

orcid logoFlorian Heyl avatar Florian Heylorcid logoMo Heydarian avatar Mo HeydarianGildas Le Corguillé avatar Gildas Le Corguilléorcid logoAnika Erxleben avatar Anika ErxlebenAnup Kumar avatar Anup Kumarorcid logoBérénice Batut avatar Bérénice Batutorcid logoLucille Delisle avatar Lucille DelisleWilliam Durand avatar William DurandMehmet Tekman avatar Mehmet Tekmanorcid logoPavankumar Videm avatar Pavankumar VidemVerena Moosmann avatar Verena MoosmannNiall Beard avatar Niall BeardMélanie Petera avatar Mélanie Peteraorcid logoArmin Dadras avatar Armin Dadrasorcid logoHelena Rasche avatar Helena RascheTorsten Houwaart avatar Torsten Houwaartorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoWolfgang Maier avatar Wolfgang MaierEkaterina Polkh avatar Ekaterina PolkhLeily Rabbani avatar Leily Rabbaniorcid logoNicola Soranzo avatar Nicola SoranzoFidel Ramirez avatar Fidel Ramirezorcid logoBjörn Grüning avatar Björn Grüningorcid logoKhaled Jum'ah avatar Khaled Jum'ahVivek Bhardwaj avatar Vivek Bhardwajorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoMartin Čech avatar Martin ČechFriederike Dündar avatar Friederike DündarDevon Ryan avatar Devon Ryanorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoMaria Doyle avatar Maria Doyleorcid logoMallory Freeberg avatar Mallory Freebergorcid logoKatarzyna Kamieniecka avatar Katarzyna KamienieckaJoachim Wolff avatar Joachim Wolff

Funding

These individuals or organisations provided funding support for the development of this resource

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CRC992
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UFR
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de.NBI
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ELIXIR Europe