Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

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Contributors

This material was contributed to by:

Gildas Le Corguillé avatar Gildas Le Corguilléorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoBérénice Batut avatar Bérénice Batutorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoMo Heydarian avatar Mo Heydarianorcid logoLucille Delisle avatar Lucille DelisleVivek Bhardwaj avatar Vivek BhardwajEkaterina Polkh avatar Ekaterina Polkhorcid logoYvan Le Bras avatar Yvan Le BrasFriederike Dündar avatar Friederike Dündarorcid logoMartin Čech avatar Martin Čechorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoMallory Freeberg avatar Mallory FreebergNiall Beard avatar Niall BeardMélanie Petera avatar Mélanie PeteraMehmet Tekman avatar Mehmet TekmanJoachim Wolff avatar Joachim Wolfforcid logoBjörn Grüning avatar Björn Grüningorcid logoHelena Rasche avatar Helena RascheAnup Kumar avatar Anup KumarLeily Rabbani avatar Leily Rabbaniorcid logoFlorian Heyl avatar Florian Heylorcid logoKatarzyna Kamieniecka avatar Katarzyna KamienieckaFidel Ramirez avatar Fidel Ramirezorcid logoArmin Dadras avatar Armin DadrasWilliam Durand avatar William Durandorcid logoMaria Doyle avatar Maria DoyleVerena Moosmann avatar Verena MoosmannDevon Ryan avatar Devon Ryanorcid logoPavankumar Videm avatar Pavankumar VidemTorsten Houwaart avatar Torsten Houwaart

Funding

These individuals or organisations provided funding support for the development of this resource

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ELIXIR Europe
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CRC992
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de.NBI
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UFR