Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

Contributors

This material was contributed to by:

Ekaterina Polkh avatar Ekaterina Polkhorcid logoArmin Dadras avatar Armin DadrasJoachim Wolff avatar Joachim Wolfforcid logoFlorian Heyl avatar Florian Heylorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoLucille Delisle avatar Lucille Delisleorcid logoYvan Le Bras avatar Yvan Le BrasVivek Bhardwaj avatar Vivek Bhardwajorcid logoMo Heydarian avatar Mo Heydarianorcid logoHelena Rasche avatar Helena Rascheorcid logoBjörn Grüning avatar Björn GrüningFidel Ramirez avatar Fidel RamirezMehmet Tekman avatar Mehmet Tekmanorcid logoBérénice Batut avatar Bérénice BatutGildas Le Corguillé avatar Gildas Le Corguilléorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoPavankumar Videm avatar Pavankumar VidemAnup Kumar avatar Anup Kumarorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoMallory Freeberg avatar Mallory FreebergTorsten Houwaart avatar Torsten HouwaartLeily Rabbani avatar Leily Rabbaniorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoKhaled Jum'ah avatar Khaled Jum'ahWilliam Durand avatar William DurandNiall Beard avatar Niall Beardorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoMartin Čech avatar Martin ČechMélanie Petera avatar Mélanie Peteraorcid logoKatarzyna Kamieniecka avatar Katarzyna KamienieckaFriederike Dündar avatar Friederike Dündarorcid logoMaria Doyle avatar Maria DoyleDevon Ryan avatar Devon RyanVerena Moosmann avatar Verena Moosmann

Funding

These individuals or organisations provided funding support for the development of this resource

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UFR
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ELIXIR Europe
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CRC992
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de.NBI