Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim WolffDevon Ryan avatar Devon Ryan

Contributors

This material was contributed to by:

Fidel Ramirez avatar Fidel Ramirezorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoPavankumar Videm avatar Pavankumar Videmorcid logoHelena Rasche avatar Helena Rascheorcid logoYvan Le Bras avatar Yvan Le BrasMélanie Petera avatar Mélanie Peteraorcid logoFlorian Heyl avatar Florian Heylorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoAnika Erxleben avatar Anika ErxlebenLeily Rabbani avatar Leily RabbaniAnup Kumar avatar Anup KumarTorsten Houwaart avatar Torsten Houwaartorcid logoMo Heydarian avatar Mo HeydarianNiall Beard avatar Niall BeardMehmet Tekman avatar Mehmet TekmanEkaterina Polkh avatar Ekaterina PolkhJoachim Wolff avatar Joachim WolffDevon Ryan avatar Devon Ryanorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoBjörn Grüning avatar Björn GrüningFriederike Dündar avatar Friederike Dündarorcid logoMallory Freeberg avatar Mallory Freebergorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoBérénice Batut avatar Bérénice Batutorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoLucille Delisle avatar Lucille DelisleVivek Bhardwaj avatar Vivek Bhardwajorcid logoMaria Doyle avatar Maria Doyle

Funding

These individuals or organisations provided funding support for the development of this resource

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UFR
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ELIXIR Europe
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de.NBI
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CRC992