Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

Contributors

This material was contributed to by:

orcid logoMallory Freeberg avatar Mallory FreebergFriederike Dündar avatar Friederike DündarTorsten Houwaart avatar Torsten Houwaartorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoBjörn Grüning avatar Björn GrüningMehmet Tekman avatar Mehmet Tekmanorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoMo Heydarian avatar Mo HeydarianLeily Rabbani avatar Leily RabbaniAnup Kumar avatar Anup Kumarorcid logoSaskia Hiltemann avatar Saskia HiltemannVivek Bhardwaj avatar Vivek Bhardwajorcid logoArmin Dadras avatar Armin DadrasVerena Moosmann avatar Verena MoosmannFidel Ramirez avatar Fidel Ramirezorcid logoLucille Delisle avatar Lucille Delisleorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoBérénice Batut avatar Bérénice Batutorcid logoHelena Rasche avatar Helena RascheJoachim Wolff avatar Joachim Wolfforcid logoMartin Čech avatar Martin Čechorcid logoMaria Doyle avatar Maria Doyleorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczEkaterina Polkh avatar Ekaterina Polkhorcid logoAnika Erxleben avatar Anika ErxlebenMélanie Petera avatar Mélanie PeteraNiall Beard avatar Niall Beardorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoPavankumar Videm avatar Pavankumar VidemGildas Le Corguillé avatar Gildas Le CorguilléDevon Ryan avatar Devon RyanWilliam Durand avatar William Durandorcid logoFlorian Heyl avatar Florian Heyl

Funding

These individuals or organisations provided funding support for the development of this resource

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UFR
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CRC992
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ELIXIR Europe
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de.NBI