Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

Contributors

This material was contributed to by:

orcid logoHelena Rasche avatar Helena Rascheorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoPavankumar Videm avatar Pavankumar Videmorcid logoFlorian Heyl avatar Florian Heylorcid logoMallory Freeberg avatar Mallory Freebergorcid logoMo Heydarian avatar Mo Heydarianorcid logoBjörn Grüning avatar Björn GrüningEkaterina Polkh avatar Ekaterina PolkhVivek Bhardwaj avatar Vivek BhardwajFidel Ramirez avatar Fidel Ramirezorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczJoachim Wolff avatar Joachim WolffNiall Beard avatar Niall Beardorcid logoWolfgang Maier avatar Wolfgang MaierTorsten Houwaart avatar Torsten HouwaartAnup Kumar avatar Anup Kumarorcid logoLucille Delisle avatar Lucille DelisleVerena Moosmann avatar Verena Moosmannorcid logoMartin Čech avatar Martin Čechorcid logoBérénice Batut avatar Bérénice BatutMélanie Petera avatar Mélanie PeteraFriederike Dündar avatar Friederike Dündarorcid logoArmin Dadras avatar Armin Dadrasorcid logoKatarzyna Kamieniecka avatar Katarzyna KamienieckaGildas Le Corguillé avatar Gildas Le CorguilléDevon Ryan avatar Devon RyanWilliam Durand avatar William Durandorcid logoNicola Soranzo avatar Nicola SoranzoLeily Rabbani avatar Leily Rabbaniorcid logoMaria Doyle avatar Maria DoyleMehmet Tekman avatar Mehmet Tekmanorcid logoKhaled Jum'ah avatar Khaled Jum'ah

Funding

These individuals or organisations provided funding support for the development of this resource

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ELIXIR Europe
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de.NBI
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CRC992
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UFR