Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

Contributors

This material was contributed to by:

orcid logoBjörn Grüning avatar Björn GrüningTorsten Houwaart avatar Torsten Houwaartorcid logoMartin Čech avatar Martin ČechVerena Moosmann avatar Verena Moosmannorcid logoMaria Doyle avatar Maria Doyleorcid logoHelena Rasche avatar Helena RascheVivek Bhardwaj avatar Vivek BhardwajEkaterina Polkh avatar Ekaterina Polkhorcid logoAnika Erxleben avatar Anika ErxlebenJoachim Wolff avatar Joachim Wolfforcid logoYvan Le Bras avatar Yvan Le Brasorcid logoArmin Dadras avatar Armin Dadrasorcid logoFlorian Heyl avatar Florian HeylNiall Beard avatar Niall Beardorcid logoKatarzyna Kamieniecka avatar Katarzyna KamienieckaGildas Le Corguillé avatar Gildas Le CorguilléLeily Rabbani avatar Leily RabbaniWilliam Durand avatar William Durandorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoBérénice Batut avatar Bérénice Batutorcid logoKhaled Jum'ah avatar Khaled Jum'ahMélanie Petera avatar Mélanie Peteraorcid logoNicola Soranzo avatar Nicola SoranzoDevon Ryan avatar Devon RyanAnup Kumar avatar Anup KumarFidel Ramirez avatar Fidel RamirezFriederike Dündar avatar Friederike DündarMehmet Tekman avatar Mehmet Tekmanorcid logoMo Heydarian avatar Mo Heydarianorcid logoLucille Delisle avatar Lucille Delisleorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoPavankumar Videm avatar Pavankumar Videmorcid logoMallory Freeberg avatar Mallory Freeberg

Funding

These individuals or organisations provided funding support for the development of this resource

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de.NBI
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UFR
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CRC992
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ELIXIR Europe