Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

Contributors

This material was contributed to by:

Mehmet Tekman avatar Mehmet TekmanFidel Ramirez avatar Fidel Ramirezorcid logoPavankumar Videm avatar Pavankumar VidemVivek Bhardwaj avatar Vivek Bhardwajorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolfforcid logoLucille Delisle avatar Lucille DelisleLeily Rabbani avatar Leily Rabbaniorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoWolfgang Maier avatar Wolfgang MaierTorsten Houwaart avatar Torsten HouwaartDevon Ryan avatar Devon RyanMélanie Petera avatar Mélanie Peteraorcid logoMaria Doyle avatar Maria DoyleNiall Beard avatar Niall BeardEkaterina Polkh avatar Ekaterina Polkhorcid logoMallory Freeberg avatar Mallory Freebergorcid logoBjörn Grüning avatar Björn Grüningorcid logoBérénice Batut avatar Bérénice BatutAnup Kumar avatar Anup Kumarorcid logoHelena Rasche avatar Helena RascheFriederike Dündar avatar Friederike Dündarorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoMo Heydarian avatar Mo Heydarian

Funding

These individuals or organisations provided funding support for the development of this resource

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ELIXIR Europe
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CRC992
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de.NBI
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UFR