Can RNA-seq techniques be applied to scRNA-seq?

Authors: orcid logoWendi Bacon avatar Wendi BaconMehmet Tekman avatar Mehmet TekmanRahmot Afolabi avatar Rahmot AfolabiAdd Contributions!

The short answer is ‘no, but yes’. At the beginning this was impossible due to the over-prevalence of dropout events (“zeroes”) in the data complicating the normalisation techniques, but this is not so much of a problem any more with newer methods.

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