DNA sequence data has become an indispensable tool for Molecular Biology & Evolutionary Biology. Study in these fields now require a genome sequence to work from. We call this a 'Reference Sequence.' We need to build a reference for each species. We do this by Genome Assembly. De novo Genome Assembly is the process of reconstructing the original DNA sequence from the fragment reads alone.


Before diving into this topic, we recommend you to have a look at:


Lesson Hands-on Slides Input dataset Galaxy tour
Introduction to Genome Assembly
De Bruijn Graph Assembly


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